Commonwealth
Biotechnologies, Inc.
911 E. Leigh St.
Richmond, VA 23219
tel: (800) 735-9224
(800) RELY-CBI
fax: (804) 648-2641
e-mail: [email protected]

----serving the biomedical research community since 1992----


CBI DNA Sequencing

High Throughput Automated DNA Sequence Analysis
ABI 377XL Prism Instrumentation
Plasmid, Phage, BAC, Viral, P1, PCR (Any Template)
!! as low as $0.10 per base !!

CBI features three basic sequencing strategies tailored to meet the needs of the individual investigator:

I. Econo Sequencing; Low cost, high throughput: CBI was first to introduce this low cost concept for high volume, single pass DNA sequencing, designed for the experienced molecular biologist or the cost-conscious scientist. You provide a colony containing a vector with the insert to sequence, we isolate the template, run a sequence reaction and forward the results to you for analysis and processing. Standard primers are available at no cost. We design and synthesize non-standard primers at our normal low rates.

    Econo-Sequencing is offered as either SS or DS sequencing. For the experienced molecular biologists, DS Econo-Sequencing is an excellent low cost alternative to comprehensive double strand sequencing.

    Econo-Sequencing is the ideal alternative for the identification of subclones or for verification of cloned PCR products.

    Custom Econo-Sequencing can be tailored to meet your project requirements. Price adjustments are available for repetitive type projects, or if you request additional services (editing, alignment, assembly, etc.). Priced per reaction or project, this guaranteed service provides sequence data for as low as $0.10 per base! Price and throughput are dependent on volume.

II. Comprehensive Sequence Analysis; accurate, publication quality, double strand sequence: CBI offers a complete sequencing service. You provide the template and we perform comprehensive double strand sequence analysis for one package price. This guaranteed service provides accurate sequence for $1-$2 per base pair or lower, depending on size and type of project.

III. Seq-AID; accurate, publishable, double strand sequence from difficult to sequence templates: CBI has great success in tackling tough-to-sequence clones. High or low GC sequences can be extremely challenging and require special techniques and attention. Our sequencing technologists have years of experience with difficult sequences, and have a very high rate of success. Please let us know before we start if you have a tough to sequence template. The price for this service will depend on the sequencing project. Please inquire.

Any template is acceptable:

If requested, template preparation can be provided, volume discounts are available.

Most sequencing projects are specialized and require a quotation.

These projects can include but are not limited to:

PCR samples

RT-PCR samples

Small genome projects

cDNA library sequencing

phage display library sequenicng

SAGE library sequencing

Mutation detection

Clinical samples

BAC clones

Please call or e-mail our specialists with the details of your project.

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